Saturday , February 16 2019

Antabuse (Disulfiram)

Generic Name: disulfiram (dye SUL fi ram)

Brand Names: Antabuse

 

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Description

The active ingredient in Antabuse is disulfiram. It acts as an antagonist to alcohol. Antabuse is available in pill form.

 

It can be found in either quantities of 250mg or 500mg.

 

How It Works

 

Disulfiram is an aldehyde dehydrogenase inhibitor. This means that it inhibits the function of this particular enzyme. The main function of disulfiram is to change the way that the body metabolizes alcohol. Normally, alcohol, once consumed, is broken down to acetaldehyde. This substance is broken down even more by the enzyme aldehyde dehydrogenase. This enzyme can be found in the liver. Simply, disulfiram prevents this enzyme from performing its function. In turn, this causes the amount of acetaldehyde present in the system to slowly accumulate and increase.

 

This causes several unpleasant, physical reactions.

 

Uses

 

Antabuse is used to treat individuals who display indicators of alcohol abuse. These people tend to consume unhealthy levels of alcohol. When such individuals take Antabuse prior to drinking any alcohol, their bodies is not able to metabolize the alcohol. This knowledge of the adverse reactions that will occur is often enough to dissuade people from drinking alcohol while taking Antabuse. The effects of Antabuse may carry on for many hours after consumption.

 

Dosage

 

You should only take Antabuse if you have been given permission by a medical expert. This professional will be able to inform you of the quantity that will be most effective for you. It is imperative that you follow these instructions, regardless of whether you feel Antabuse is working or not. Avoid changing the amount of Antabuse that you need to take unless you have spoken to a doctor. You should not give Antabuse to someone before first informing them of what they are taking.

 

The most common quantities that are prescribed are usually between 250 and 500mg of Antabuse. This is taken as just one dose. It is usually recommended to be taken in the morning. However, if you experience any drowsiness due to the Antabuse, you can take it in the evening.

 

Side Effects

 

Every person reacts differently when taking Antabuse. Some individuals may have some negative effects when taking Antabuse.

 

Some of the symptoms you can expect are:

 

 Sleepiness
 Reduced sexual performance in men
 Headache
 Odd taste in the mouth
 Skin irritation
 Tiredness
 Eye pain
 Changes in ability to see
 Transformation in temperament
 Unusual sensations in limbs or extremities

 

Precautions

 

Do not take Antabuse if:

 

 You have drunk alcohol within the last twelve hours
 You are allergic to disulfiram
 You have consumed paraldehyde or metronidazole
 You have recently had any foods or substances that may contain trace amounts of alcohol

 

You should tell a medical expert if you have:

 

 Been diagnosed with liver or kidney disorders
 Previously experienced heart issues
 An thyroid gland that is not working properly
 Diabetes
 Any issues with your brain or head
 Seizures
 Psychiatric conditions
 Have rubber allergies
 Are taking any medications or treatments

 

Self-Care

 

It is important that you do not drink alcohol while taking Antabuse. Even if you are no longer taking Antabuse, you should wait at least two weeks before consuming alcohol once more.

 

It has not been established yet if Antabuse can pass to unborn children or through breast milk. If you are either an expectant mother or will be breastfeeding, you should first speak to a medical expert.

 

You should get the advice of a doctor before giving Antabuse to those who are under the age of eighteen.

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